[HTML][HTML] Antigen-specificity measurements are the key to understanding T cell responses
… approaches to studying antigen-specific T cells and their specific … repertoire in a given
individual, without prior knowledge of … allowed identification of the TCRs that were antigen-specific, …
individual, without prior knowledge of … allowed identification of the TCRs that were antigen-specific, …
T cell antigen discovery
AV Joglekar, G Li - Nature methods, 2021 - nature.com
… CD8 + T cells in the non-obese diabetic mouse 25 . Another … b, Flow cytometric identification
of antigen-specific T cells via … methods do not require a priori knowledge of the antigen, but …
of antigen-specific T cells via … methods do not require a priori knowledge of the antigen, but …
Production and use of antigen tetramers to study antigen-specific B cells
A Phelps, D Pazos-Castro, F Urselli, E Grydziuszko… - Nature …, 2024 - nature.com
… identification of rare antigen-specific B cells. The selected … CD4 + T cells, some of these
fates can be accessed in a T cell-… -based technique to quantify the average biotin:antigen ratio, …
fates can be accessed in a T cell-… -based technique to quantify the average biotin:antigen ratio, …
An empirical antigen selection method identifies neoantigens that either elicit broad antitumor T-cell responses or drive tumor growth
H Lam, LK McNeil, H Starobinets, VL DeVault… - Cancer discovery, 2021 - AACR
… to neoantigen peptides by ELISpot analysis on mouse … potentially deleterious antigen-specific
immune modulation by T cells, … ; however, the frequent identification of Inhibigens in many …
immune modulation by T cells, … ; however, the frequent identification of Inhibigens in many …
T‐cell activation–induced marker assays in health and disease
C Poloni, C Schonhofer, S Ivison… - … and Cell Biology, 2023 - Wiley Online Library
… Identification of antigen-specific T cells allows for the precise … , antigen-specific T cell responses
have been quantified by … prior knowledge of epitopes and their HLA restriction is needed. …
have been quantified by … prior knowledge of epitopes and their HLA restriction is needed. …
Measuring anti-islet autoimmunity in mouse and human by profiling peripheral blood antigen-specific CD4 T cells
S Sharma, X Tan, J Boyer, D Clarke… - Science translational …, 2023 - science.org
… cell response except that it is not absolutely required for beta … Before inclusion of at-risk
individuals, this granular profiling … that circulating antigen-specific CD4 T cells are reliable …
individuals, this granular profiling … that circulating antigen-specific CD4 T cells are reliable …
In Vivo Stimulation of Therapeutic Antigen‐Specific T Cells in an Artificial Lymph Node Matrix
… quantified the fluorescence of each cell marker for every cell … Similar to our observation in
the murine antigen-specific … Cell type identification was done following the strategies we have …
the murine antigen-specific … Cell type identification was done following the strategies we have …
[HTML][HTML] Induction of antigen-specific tolerance by hepatic AAV immunotherapy regardless of T cell epitope usage or mouse strain background
GD Keeler, CD Gaddie, AS Sagadevan… - … Therapy Methods & …, 2023 - cell.com
… In vivo induction of antigen (Ag)-specific regulatory T cells (… immunotherapy that does not
require prior knowledge of the … immunotherapy that restores Ag-specific tolerance needs to …
require prior knowledge of the … immunotherapy that restores Ag-specific tolerance needs to …
In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography
AW Woodham, SH Zeigler, EL Zeyang, SC Kolifrath… - Nature …, 2020 - nature.com
… CD8 + T cells by positron emission tomography in mice bearing … identity in vivo, as these
approaches do not exploit the … f, Quantification of synTac PET signals in the lungs before (black…
approaches do not exploit the … f, Quantification of synTac PET signals in the lungs before (black…
The role of B cell antigen presentation in the initiation of CD4+ T cell response
Z Hua, B Hou - Immunological reviews, 2020 - Wiley Online Library
… in vitro assay in which cloned antigen-specific T cells were … Nevertheless, the identification
of Toll in drosophila as a key … + T cell activation by measuring in vitro IL-2 production of the …
of Toll in drosophila as a key … + T cell activation by measuring in vitro IL-2 production of the …